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Mouse Phospholipase A2, Group III (PLA2G3) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Phospholipase A2, Group III (PLA2G3) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PLA2G3 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Group 3 secretory phospholipase A2 is a calcium-dependent enzyme that primarily targets extracellular phospholipids, hydrolyzing the ester bond of the fatty acyl group at the sn-2 position without specific head group selectivity. PLA2G3 is extensively expressed in mice, particularly in inflammation-related tissues such as the skin, lungs, and intestines. Research indicates that PLA2G3 promotes the formation of macrophage foam cells by hydrolyzing phosphatidylcholine (PC), thereby worsening atherosclerosis. Additionally, in the skin, overexpression of PLA2G3 results in skin inflammation, characterized by dermatitis, pustules, keratinization of hair follicles, and eosinophil infiltration.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.