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Mouse Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PPARgC1a in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) functions as a transcriptional coactivator for steroid and nuclear receptors. It significantly enhances the transcriptional activity of PPARG and the thyroid hormone receptor on the uncoupling protein promoter. PGC-1α is widely involved in the regulation of energy metabolism and mitochondrial biogenesis. In mouse skeletal muscle, PGC-1α substantially boosts mitochondrial number and function by upregulating the expression of genes associated with mitochondrial performance, including the activity of mitochondrial respiratory chain complex IV and markers of mitochondrial biogenesis.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Hatazawa, Yukino et al. "Metabolomic Analysis of the Skeletal Muscle of Mice Overexpressing PGC-1α." PloS one vol. 10,6 e0129084. 26 Jun. 2015.