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Mouse Peptidyl Arginine Deiminase Type II (PADI2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Peptidyl Arginine Deiminase Type II (PADI2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PADI2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Protein-arginine deiminase type-2 (PADI2) facilitates the deimination of arginine residues in proteins. Abnormal expression of PADI2 in the central nervous system can contribute to neurodegenerative diseases, with its overexpression linked to demyelination in mice. Additionally, irregular PADI2 activity may influence neuron differentiation and function. PADI2 plays a role in various biological processes, including the regulation of stem cell pluripotency, as well as cell proliferation and differentiation. Given its critical role in multiple diseases, PADI2 inhibitors are being explored as potential treatments for autoimmune disorders and cancer.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Tsuji-Hosokawa, Atsumi et al. "Peptidyl arginine deiminase 2 (Padi2) is expressed in Sertoli cells in a specific manner and regulated by SOX9 during testicular development." Scientific reports vol. 8,1 13263. 5 Sep. 2018.