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Mouse Paraoxonase 2 (PON2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Paraoxonase 2 (PON2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PON2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Serum paraoxonase/arylesterase 2 can hydrolyze lactones and various aromatic carboxylic acid esters. In mice, Pon2 plays diverse biological roles, particularly in antioxidation, anti-inflammation, protection of neural and retinal functions, and regulation of the hematopoietic system. In an atherosclerosis model, Pon2-deficient mice exhibited increased oxidative stress and more pronounced atherosclerotic plaque formation. Pon2 influences mitochondrial function by binding to mitochondrial respiratory chain complex III, which reduces the production of reactive oxygen species (ROS). Additionally, Pon2-deficient mice displayed heightened inflammatory responses during atherosclerosis, including elevated macrophage activity and lipid peroxide levels.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.