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Mouse Norepinephrine Transporter (NET) ELISA Kit-Sandwich

Cat. No.EK6F488

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Norepinephrine Transporter (NET) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse NET in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Norepinephrine Transporter (NET).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

The sodium-dependent noradrenaline transporter, also known as the norepinephrine transporter (NET), in mice operates in a manner similar to its human version. It is primarily responsible for the reuptake of norepinephrine through the combined action of sodium ion gradients and chloride ions. Dysfunction in NET is linked to various health conditions, including hypertension, depression, and other neurological disorders. Studies indicate that changes in NET activity can cause abnormal norepinephrine levels, which affect blood pressure regulation and mood. In mice, NET plays a role in regulating norepinephrine concentration in the synaptic cleft, thereby influencing neurotransmission and behavioral responses.

Target/Biomarker Mouse NET
Target Synonym SLC6A2; NAT1; NET; NET1; Sodium-dependent noradrenaline transporter; Noradrenaline Transporter; Solute Carrier Family 6 member 2; Neurotransmitter transporter; Noradrenalin
Gene ID 20538
UniProt ID O55192

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Góral, Izabella et al. "Structure Modeling of the Norepinephrine Transporter." Biomolecules vol. 10,1 102. 7 Jan. 2020.
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