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Mouse Neuronal Pentraxin I (NPTX1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Neuronal Pentraxin I (NPTX1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse NPTX1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Neuronal pentraxin-1 (NP1) may play a role in mediating the uptake of synaptic material during synapse remodeling or in facilitating the synaptic clustering of AMPA glutamate receptors at certain excitatory synapses. As a pro-apoptotic protein induced by low potassium levels, NP1 is crucial in the process of neuronal death in the mouse brain. Research indicates that NP1 expression is significantly upregulated under low potassium conditions, and using RNA interference technology to inhibit NP1 expression can reduce cell death. Additionally, in a mouse brain hypoxia-ischemia model, NP1 expression is notably increased in the CA1 and CA3 regions of the hippocampus, suggesting its key role in neuronal damage and death.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.