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Mouse Myosin VA (MYO5A) ELISA Kit-Sandwich

Cat. No.EK5F942

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Myosin VA (MYO5A) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MYO5A in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Myosin VA (MYO5A).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Myosin-Va is a processive actin-based motor capable of undertaking large steps that approximate the 36-nm pseudo-repeat of the actin filament. It plays a role in transporting melanosomes and mediates vesicle transport to the plasma membrane. Additionally, it might be necessary for polarization processes involved in dendrite formation. Myosin Va is abundantly expressed in the mouse brain, especially in the pyramidal neurons of the hippocampus. It is crucial for postsynaptic trafficking and light membrane fractionation, both vital for neuronal signaling. In the dilute-lethal (d-n) mouse model, the absence of Myosin Va results in severe neurodevelopmental disorders, including ataxia, intellectual disability, and epileptic seizures.

Target/Biomarker Mouse MYO5A
Target Synonym GS1; MYH12; MYO5; MYOXIN; MYR12; myosin V; myosin Va; Myosin;Heavy Polypeptide Kinase; Myosin Heavy Chain 12; Myoxin; Myosin V; Dilute myosin heavy chain; non-muscle
Gene ID 17918
UniProt ID Q99104

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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