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Mouse Mitochondrial Open Reading Frame Of The 12S rRNA-c (MOTS-c) ELISA Kit-Competitive
Product Overview
BioVenic Mouse Mitochondrial Open Reading Frame Of The 12S rRNA-c (MOTS-c) ELISA Kit-Competitive is designed for the quantitative determination of Mouse MOTS-c in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.
Specifications
Target Information
Mitochondrial Open Reading Frame of The 12S rRNA-c (MOTS-c) is a peptide encoded by mitochondrial DNA that exhibits multifaceted metabolic regulatory effects in mice. This 16-amino-acid peptide promotes metabolic homeostasis, enhances insulin sensitivity, and regulates energy metabolism primarily by activating the AMPK signaling pathway. By activating AMPK (adenosine monophosphate-activated protein kinase), MOTS-c improves insulin sensitivity. Research has demonstrated that MOTS-c can mitigate insulin resistance and obesity caused by a high-fat diet in mice. Moreover, its expression in skeletal muscle is linked to muscle mass and declines with age, emphasizing its crucial role in maintaining muscle health and metabolic balance.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.