Mouse Milk Fat Globule EGF Factor 8 (MFGE8) ELISA Kit-Sandwich

Lactadherin aids in the phagocytic clearance of apoptotic cells across various tissues. It acts as a specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors and can bind to phosphatidylserine-rich cell surfaces independently of receptors. It plays a crucial role in maintaining intestinal epithelial homeostasis and promoting mucosal healing, as well as fostering VEGF-dependent neovascularization. In mice, lactadherin has diverse functions, such as enhancing the removal of platelet microvesicles, inhibiting coagulation, participating in tumor growth regulation, aiding in the clearance of neurotoxic substances, and modulating the immune system. In tumor research, lactadherin has been shown to decrease tumor size. For instance, in a mouse lung cancer model, the introduction of lactadherin significantly reduced tumor volume.