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Mouse Methylmalonic Acid (MMA) ELISA Kit-Competitive

Cat. No.EK5F93

Product TypeAnimal Immunoassay Kits

Size 96T

Product Overview

BioVenic Mouse Methylmalonic Acid (MMA) ELISA Kit-Competitive is designed for the quantitative determination of Mouse MMA in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive
Specificity The assay kit is specific for Mouse Methylmalonic Acid (MMA).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Methylmalonic acid (MMA) is a chemical compound belonging to the group of dicarboxylic acids. It is composed of the fundamental structure of malonic acid with an added methyl group. The salts formed from methylmalonic acid are known as methylmalonates. The functions of MMA in mice are mainly reflected in its role as a biomarker of vitamin B12 deficiency, its effects on the nervous system and energy metabolism, and its interactions with other metabolic pathways. Research has demonstrated that a humanized partial rescue mouse model of methylmalonic aciduria can facilitate the assessment of long-term pathophysiological effects associated with elevated levels of methylmalonic acid.

Target/Biomarker Mouse MMA
Target Synonym MMA; Methylmalonic Acid

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Peters, Heidi L et al. "Mouse models for methylmalonic aciduria." PloS one vol. 7,7 (2012): e40609.
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