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Mouse Maresin 1 (MaR1) ELISA Kit-Competitive

Cat. No.EK5F76

Product TypeAnimal Immunoassay Kits

Size 96T

Product Overview

BioVenic Mouse Maresin 1 (MaR1) ELISA Kit-Competitive is designed for the quantitative determination of Mouse MaR1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.

Specifications

Assay Type ELISA-Competitive
Specificity The assay kit is specific for Mouse Maresin 1 (MaR1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Maresin 1 (Mar1) is a novel pro-resolving mediator known for its strong anti-inflammatory effects across several animal models. MaR1 has multiple biological functions in mouse models, including anti-inflammation, pro-inflammatory resolution, regulation of immune response, improvement of bone metabolism and neuroprotection. Research involving mice has shown that Mar1 offers protective benefits in sepsis by reducing LPS and bacterial burden in the serum, inhibiting inflammatory responses, and enhancing the function of vital organs. In osteoporosis models, MaR1 improves bone regeneration by reducing inflammation and fibrosis. Studies have shown that MaR1 can reduce aging-related inflammation, promote bone formation, and enhance the rigidity of bone structure.

Target/Biomarker Mouse MaR1
Target Synonym 7(R)-Maresin 1; quinolin-7-ol; 7-hydroxychinoline; (4Z;7R;8E;10E;12Z;14S;16Z;19Z)-7;14-Dihydroxy-4;8;10;12;16;19-docosahexaenoic acid; 7-Chinolinol; 7R;14S-dihydroxydocosa-4Z;8E;10E;12Z;16Z;19Z-hexaenoic acid; 4;8;10;12;16;19-Docosahexaenoic acid; 7;14-dihydroxy-; (4Z;7R;8E;10E;12Z;14S;16Z;19Z)-; 7-Quinolinol; 7-HYDROXYQUINOLINE; 7R-maresin-1; 7-hydoxyquinoline

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Li, Ruidong et al. "Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis." Mediators of inflammation vol. 2016 (2016): 3798465.
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