Mouse Mannose Receptor C Type 2 (MRC2) ELISA Kit-Sandwich

C-type mannose receptor 2 is believed to function as an endocytic lectin receptor with calcium-dependent lectin activity. It facilitates the internalization of glycosylated ligands from the extracellular space, releasing them in an endosomal compartment via clathrin-mediated endocytosis. It may also participate in the plasminogen activation system by controlling the extracellular levels of PLAUR/PLAU, thereby potentially regulating protease activity at the cell surface. In mice, MRC2 is involved in diverse biological processes, such as cell proliferation, apoptosis, inflammatory response, and disease progression, with its specific role varying according to the tissue and disease context. MRC2 is expressed in various mouse tissues, including the spleen, myocardium, and skin. Research indicates that MRC2 expression decreases with age, possibly impacting the regulation of collagen degradation in tissues.