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Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit-Sandwich

Cat. No.EK5F189

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MIP1a in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Macrophage Inflammatory Protein 1 Alpha (MIP1a).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

C-C motif chemokine 3, also known as CCL3, is a monokine with inflammatory and chemokinetic properties that binds to receptors CCR1, CCR4, and CCR5. It is among the key HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha can inhibit various strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) in a dose-dependent manner. In mice, CCL3 plays roles in a range of biological processes, including immune cell migration, inflammatory responses, neuroprotection, tumor progression, and fibrosis. It contributes to the inflammatory response by recruiting immune cells like neutrophils and monocytes. For instance, in diabetic obese mice, CCL3 expression correlates with the upregulation of multiple inflammatory factors, including IL-6 and CCL2.

Target/Biomarker Mouse MIP1a
Target Synonym MIP1 Alpha; CCL3; MIP1-A; SCYA3; Chemokine C-C-Motif Ligand 3; Small Inducible Cytokine A3; Homologous To Mouse Mip-1a; Tonsillar Lymphocyte LD78 Alpha Protein
Gene ID 20302
UniProt ID P10855

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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