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Mouse Lymphocyte Function Associated Antigen 1 Alpha (LFA1a) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Lymphocyte Function Associated Antigen 1 Alpha (LFA1a) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse LFA1a in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
In mice, the primary function of lymphocyte function-associated antigen 1 (LFA-1) involves cell adhesion and migration, playing a crucial role in both immune and inflammatory responses. LFA-1 is a cell surface glycoprotein composed of non-covalently bound α and β chains, creating an α1β1 structure. The molecular weight of the α chain is approximately 170 kDa, while the β chain is about 95 kDa. LFA-1 is expressed on T cells, B cells, and numerous bone marrow-derived cells, but it is absent on non-lymphocytes such as macrophages and non-lymphoid tissues. Its primary ligand is intercellular adhesion molecule-1 (ICAM-1), and the interaction between LFA-1 and ICAM-1 is crucial for T cell activation, migration, and the overall immune response.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.