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Mouse Lipase-Like PAD4 (PAD4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Lipase-Like PAD4 (PAD4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PAD4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Lipase-like PAD4 is a probable lipase essential for the accumulation of salicylic acid downstream of MPK4, enhancing plant innate immunity against invasive biotrophic pathogens and defense mechanisms upon recognizing microbe-associated molecular patterns (MAMPs). Additionally, PAD4 serves as a key enzyme in the release of neutrophil extracellular traps (NETs), which are mesh structures composed of deacetylated and citrullinated histones used to capture and kill bacteria. In mouse models, PAD4 knockout (PAD4−/−) mice exhibit significantly reduced resistance to bacterial infections, such as M1 ΔSda1 GAS, leading to larger lesions and higher bacterial counts. This indicates that PAD4 is crucial for effective bacterial clearance.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.