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Mouse Leucine Rich Alpha-2-Glycoprotein 1 (LRG1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Leucine Rich Alpha-2-Glycoprotein 1 (LRG1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse LRG1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
LRG1 has been found to be closely linked with angiogenesis in mouse tumor models. Research indicates that LRG1 can stabilize tumor blood vessels by promoting endothelial cell coverage and enhancing vascular function, thus limiting the effectiveness of immunotherapy. Additionally, inhibiting LRG1 can significantly enhance the efficacy of chemotherapy drugs like cisplatin and immune checkpoint inhibitors, such as PD-1 antibodies. As an adiponectin, LRG1 plays a significant role in obesity and insulin resistance. Overexpression of LRG1 can improve glucose homeostasis and decrease systemic inflammation in obese mice. Furthermore, LRG1 enhances neurological function in mice with cerebral ischemia-reperfusion injury by modulating the blood-brain barrier and exerting anti-inflammatory effects.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Ruan, Zhaohui et al. "Single-cell RNA sequencing unveils Lrg1's role in cerebral ischemia‒reperfusion injury by modulating various cells." Journal of neuroinflammation vol. 20,1 285. 30 Nov. 2023.