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Mouse Left/Right Determination Factor 1 (LEFTY1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Left/Right Determination Factor 1 (LEFTY1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse LEFTY1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Left-right determination factor 1 is essential for establishing the left-right axis, acting as a regulator of LEFTY2 and NODAL. In mice, Lefty1 has extensive functions, ranging from embryonic development to adult tissue repair. In mouse embryonic stem cells (mESCs), Lefty1 and Lefty2 together regulate the balance between self-renewal and pluripotent differentiation of stem cells. Specifically, Lefty1 inhibits the phosphorylation of Smad2/3, thereby suppressing the Nodal/Activin signaling pathway and promoting stem cell differentiation. Conversely, knocking down Lefty1 results in reduced stem cell differentiation and increased self-renewal capacity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.