This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Kelch Like ECH Associated Protein 1 (KEAP1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Kelch Like ECH Associated Protein 1 (KEAP1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse KEAP1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Kelch-like ECH-associated protein 1 (Keap1) serves as a substrate-specific adapter within the BTB-CUL3-RBX1 E3 ubiquitin ligase complex, playing a pivotal role in the oxidative stress response by facilitating the ubiquitination of NFE2L2/NRF2. Mice lacking Keap1 experience early death due to hyperkeratosis in the upper gastrointestinal tract, underscoring Keap1's importance in maintaining epithelial barrier integrity. However, this condition can be partially remedied through transcription factor-driven Keap1 expression, such as KRD-driven Keap1, revealing that proper Keap1 expression levels are crucial for normal cellular function.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.