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Mouse Kallikrein 1 (KLK1) ELISA Kit-Competitive
Product Overview
BioVenic Mouse Kallikrein 1 (KLK1) ELISA Kit-Competitive is designed for the quantitative determination of Mouse KLK1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Competitive ELISA method. For research use only.
Specifications
Target Information
Glandular kallikreins are enzymes that cut Met-Lys and Arg-Ser bonds in kininogen to produce Lys-bradykinin. Given its diverse biological functions, KLK1 is being explored as a promising therapeutic target for various diseases. For instance, KLK1 gene therapy has been shown to alleviate symptoms in diabetes, cardiovascular disease, and kidney disease, as well as promote angiogenesis when used topically. In studies involving mice on a high-aldosterone salt diet, those lacking KLK1 displayed elevated blood pressure and heart enlargement, indicating KLK1's significant role in combating high aldosterone-induced hypertension.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Ortega-Loubon, Christian et al. "Genetic Susceptibility to Acute Kidney Injury." Journal of clinical medicine vol. 10,14 3039. 8 Jul. 2021.