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Mouse IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse IQ Motif Containing GTPase Activating Protein 1 (IQGAP1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IQGAP1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Ras GTPase-activating-like protein IQGAP1 plays a pivotal role in regulating the dynamics and assembly of the actin cytoskeleton. It is recruited to the cell cortex through interaction with ILK, enabling it to collaborate with its effector DIAPH1 to locally stabilize microtubules, facilitating stable insertion of caveolae into the plasma membrane. In the mouse brain, IQGAP1 regulates the NR2A signaling pathway and dendritic spine density, thus impacting cognitive function. Mice lacking IQGAP1 exhibit significant impairment in the NR2A signaling pathway, reduced dendritic spine density, and deficiencies in memory formation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.