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Mouse Involucrin (iNV) ELISA Kit-Sandwich

Cat. No.EK5F770

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Involucrin (iNV) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse iNV in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Involucrin (iNV).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Involucrin is a component of the insoluble cornified cell envelope (CE) found in stratified squamous epithelia. It is produced during keratinocyte differentiation and plays a crucial role in the cornified envelope of the epidermis and other squamous epithelia. This structure is vital for maintaining the skin barrier function, providing a physical shield to prevent water loss and protect against environmental aggressors. Mice lacking involucrin show immune responses similar to atopic dermatitis, including reduced infiltration of T cells and γδT cells, suggesting that the absence of involucrin may influence the composition of the skin's immune microenvironment.

Target/Biomarker Mouse iNV
Target Synonym IVL
UniProt ID P48997

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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