This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Interleukin 8 Receptor Beta (IL8Rb) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Interleukin 8 Receptor Beta (IL8Rb) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IL8Rb in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
C-X-C chemokine receptor type 2, encoded by the Cxcr2 gene in mice, is a receptor for interleukin-8 (IL-8), a potent chemotactic factor for neutrophils. IL8Rb and IL8RA are co-expressed on the surface of neutrophils and act selectively through different ligands. IL8RA is more likely to bind IL8, while IL8RB is more likely to bind NAP-2 and GROα. When IL-8 binds to this receptor, it triggers the activation of neutrophils through a G-protein-mediated pathway that activates a phosphatidylinositol-calcium second messenger system. The receptor binds IL-8, as well as CXCL3, GRO/MGSA, and NAP-2 with high affinity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.