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Mouse Interleukin 33 (IL33) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Interleukin 33 (IL33) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IL33 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Interleukin-33 (IL-33) is a cytokine that interacts with the IL1RL1/ST2 receptor, triggering the activation of NF-kappa-B and MAPK signaling pathways in target cells. It plays a role in the maturation of Th2 cells by inducing the secretion of T-helper type 2 cytokines. In mice, IL-33 has diverse functions, including supporting nervous system development and participating in various immune regulatory and inflammatory responses. In a colorectal cancer model, IL-33 facilitates tumor progression by recruiting ST2+ TILs and boosting their activity. In a skin infection model, IL-33 combats Staphylococcus aureus growth by inducing inducible nitric oxide synthase (iNOS) expression and enhancing macrophages' antibacterial capabilities.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Li, Changwei et al. "Interleukin-33 increases antibacterial defense by activation of inducible nitric oxide synthase in skin." PLoS pathogens vol. 10,2 e1003918. 20 Feb. 2014.