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Mouse Interleukin 31 (IL31) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Interleukin 31 (IL31) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IL31 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Interleukin-31 (IL-31) activates STAT3, and potentially STAT1 and STAT5, via the IL-31 heterodimeric receptor, which consists of IL31RA and OSMR. It may play a role in skin immunity. In mice, IL-31 primarily induces itch, promotes skin inflammation, and interacts with pain pathways. IL-31 can significantly increase itching behavior and trigger severe skin inflammatory reactions when injected into the skin or directly into the spinal cord. Additionally, IL-31 mediates itch by influencing ion channels such as TRPV1 and TRPA1 and can exacerbate skin inflammation by inducing the expression of IL-17 and other inflammatory factors.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.