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Mouse Interleukin 18 (IL18) ELISA Kit-Sandwich

Cat. No.EK5F401

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Interleukin 18 (IL18) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IL18 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Interleukin 18 (IL18).
Target Species Mouse
Species Reactivity Mouse
Detection Range 125-8000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Interleukin-18 (IL-18) is a pro-inflammatory cytokine primarily involved in epithelial barrier repair, and in regulating polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. When IL-18 binds to IL18R1 and IL18RAP, it forms a signaling ternary complex that activates NF-kappa-B, leading to the synthesis of inflammatory mediators. In mice, IL-18 enhances immune responses, regulates inflammation, influences metabolism, and participates in disease development. IL-18 is also crucial in combating fungal infections, such as by restoring the Th1 immune response in Caspase-1-deficient mice.

Target/Biomarker Mouse IL18
Target Synonym IL-18;IGIF; IL-1g; IL1F4; IL1-F4; Interferon-Gamma-Inducing Factor; Interleukin-1 Family Member 4; Iboctadekin; Interleukin-1 Gamma
Gene ID 16173
UniProt ID P70380

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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