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Mouse Inter Alpha-Globulin Inhibitor H4 (ITIH4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Inter Alpha-Globulin Inhibitor H4 (ITIH4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ITIH4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Inter alpha-trypsin inhibitor, heavy chain 4, is a type II acute-phase protein (APP) that plays a role in inflammatory responses to trauma and may contribute to liver development or regeneration. In experimental arthritis, such as the pGIA model, levels of ITIH4 and its carboxylated form (cit-ITIH4) significantly increase in joint fluid and serum, correlating with disease activity. Additionally, ITIH4 shows an upregulation trend in a colitis mouse model, indicating its potential involvement in intestinal inflammation. In certain contexts, such as septic mice, ITIH4 acts as a negative acute phase protein, with concentrations decreasing following infection, suggesting that its role may vary across different inflammatory scenarios.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.