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Mouse Insulin Receptor Substrate 1 (IRS1) ELISA Kit-Sandwich

Cat. No.EK6F344

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Insulin Receptor Substrate 1 (IRS1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IRS1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Insulin Receptor Substrate 1 (IRS1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Insulin receptor substrate 1 (IRS-1) is a signaling adapter protein involved in signal transduction from the insulin receptor (INSR) and insulin-like growth factor I receptor (IGF1R), playing a crucial role in development, growth, glucose homeostasis, and lipid metabolism. In mice, IRS-1 is pivotal in insulin signaling, regulating energy metabolism, growth and development, and disease resistance. Mice lacking IRS-1 exhibit abnormal glucagon secretion, leading to elevated blood sugar levels. Additionally, IRS-1 is essential for growth and development, as systemic IRS-1 knockout mice show growth retardation, weight loss, and abnormal bone development.

Target/Biomarker Mouse IRS1
Target Synonym HIRS1
Gene ID 16367
UniProt ID P35569

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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