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Mouse Insulin Like Growth Factor Binding Protein 1 (IGFBP1) ELISA Kit-Sandwich

Name: Mouse Insulin Like Growth Factor Binding Protein 1 (IGFBP1) ELISA Kit-Sandwich
SKU: EK5F397
Rating: 5 (1 reviews)

Cat. No.EK5F397

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Mouse Insulin Like Growth Factor Binding Protein 1 (IGFBP1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IGFBP1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse Insulin Like Growth Factor Binding Protein 1 (IGFBP1).

Target Species Mouse

Species Reactivity Mouse

Detection Range 0.17-10 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Insulin-like growth factor-binding protein 1 (IGFBP1) is a multifunctional protein crucial for regulating the availability of insulin-like growth factors (IGFs) such as IGF1 and IGF2 to their receptors. This regulation influences IGF-mediated cellular processes, including cell migration, proliferation, differentiation, and apoptosis, in a cell-type specific manner. In mice, IGFBP1 plays diverse roles, including involvement in metabolism, liver protection, bone health, reproductive function, and cardiovascular protection. In models of hepatic steatosis (MASLD), exogenous IGFBP1 supplementation has been shown to improve hepatic steatosis and lower serum ALT and AST levels, highlighting its potential role in liver metabolic regulation.

Target/Biomarker Mouse IGFBP1

Target Synonym IBP1; AFBP; IGF-BP25; PP12; Placental Protein 12; Amniotic Fluid Binding Protein; Alpha-Pregnancy-Associated Endometrial Globulin; Growth Hormone Independent-Binding Protein

Gene ID 16006

UniProt ID P47876

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Mak, Anne Linde et al. "Anaerobutyricum soehngenii Reduces Hepatic Lipogenic Pathways and Increases Intestinal Gluconeogenic Gene Expression in Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD) Mice." International journal of molecular sciences vol. 25,6 3481. 20 Mar. 2024.