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Mouse Immunoglobulin G (IgG) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Immunoglobulin G (IgG) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IgG in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
In mice, the function of immunoglobulin G (IgG) is intricately linked to its interaction with Fcγ receptors (FcγRs). This interaction is pivotal in various immune responses, including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, and the clearance of immune complexes. Fcγ receptors are a crucial class of cell surface receptors in the immune system, capable of recognizing and binding to the Fc fragment of IgG. Research has highlighted significant differences in the structure and function of Fcγ receptors between mice and humans. By binding to Fcγ receptors, IgG can enhance ADCC, facilitating the clearance of pathogens or damaged cells.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Katano, Ikumi et al. "Improved Detection of in vivo Human NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Using a Novel NOG-FcγR-Deficient Human IL-15 Transgenic Mouse." Frontiers in immunology vol. 11 532684. 7 Oct. 2020.