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Mouse Immunoglobulin E (IgE) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Immunoglobulin E (IgE) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IgE in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
In mice, Immunoglobulin E (IgE) is primarily responsible for mediating type 1 hypersensitivity reactions, which play a critical role in defending against helminth parasites. When allergens or parasites are encountered, IgE binds to FcεRI receptors on mast cells and basophils. This binding, followed by antigen crosslinking, triggers degranulation and the release of inflammatory mediators like histamine, leading to symptoms such as bronchoconstriction and increased vascular permeability. IgE also plays a role in antigen presentation and can influence immune responses, although its role in non-parasitic immunity is less significant compared to other isotypes. In mice, excessive production of IgE may enhance the immune response against tumors.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.