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Mouse Histone Deacetylase 6 (HDAC6) ELISA Kit-Sandwich

Cat. No.EK6F451

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Histone Deacetylase 6 (HDAC6) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse HDAC6 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Histone Deacetylase 6 (HDAC6).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Protein deacetylase HDAC6 targets a broad array of non-histone substrates for deacetylation. It is pivotal in microtubule-dependent cell movement by mediating the deacetylation of tubulin and is essential for cilia disassembly through the deacetylation of alpha-tubulin. HDAC6 is highly expressed in the mouse brain, particularly in regions such as the dorsal habenula, hippocampus, and motor cortex, which are closely linked to emotional behavior. Research demonstrates that HDAC6's deacetylation activity significantly influences the emotional behavior of mice. Mice lacking HDAC6 show reduced anxiety, enhanced depressive-like behaviors, and increased activity.

Target/Biomarker Mouse HDAC6
Target Synonym HD6; JM21
Gene ID 15185
UniProt ID Q9Z2V5

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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