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Mouse Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Hepatitis A Virus Cellular Receptor 2 (HAVCR2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse HAVCR2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Hepatitis A virus cellular receptor 2 homolog is a cell surface receptor involved in modulating both innate and adaptive immune responses, typically with an inhibitory function. Some reports suggest that it may also have stimulating functions, which could depend on the cellular context or the specific ligand involved. HAVCR2 is expressed in various tumor cells and, by binding to the ligand galectin-9, it negatively regulates Th1/Th1 cell functions, leading to apoptosis. This action plays a crucial role in counteracting tumor growth and preventing immune escape. For instance, studies have demonstrated that knocking out the HAVCR2 gene (as in HAVCR2*fl/fl mice) can enhance anti-tumor immune responses and inhibit tumor growth.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.