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Mouse Hemicentin 1 (HMCN1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Hemicentin 1 (HMCN1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse HMCN1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Hemicentin-1 is pivotal in the transformation of the podocyte cytoskeleton mediated by transforming growth factor beta, leading to the reduction of F-actin fibers and causing podocytes to broaden, flatten, and elongate. It is essential for the organization of the basement membrane. In hemicentin-1-deficient mouse embryos, cells fail to complete cytokinesis, resulting in multinucleation. During tooth development, hemicentin-1 is crucial for root formation by promoting the differentiation of mesenchymal cells. Research indicates that during the development of mouse incisors and molars, HMCN1 expression is spatiotemporally specific, and knocking down HMCN1 hampers dentinogenesis and the migration of dental pulp cells.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.