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Mouse H2A Histone Family, Member X (H2AFX) ELISA Kit-Sandwich

Cat. No.EK5F36

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse H2A Histone Family, Member X (H2AFX) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse H2AFX in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse H2A Histone Family, Member X (H2AFX).
Target Species Mouse
Species Reactivity Mouse
Detection Range 31.25-2000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Histone H2AX is a variant of histone H2A that substitutes for conventional H2A in certain nucleosomes. These nucleosomes wrap and compact DNA into chromatin, thus limiting DNA accessibility to cellular processes that use DNA as a template. Consequently, histones are crucial for transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is controlled by a complex array of post-translational histone modifications, known as the histone code, along with nucleosome remodeling. In mice, the H2ax gene encodes this protein.

Target/Biomarker Mouse H2AFX
Target Synonym H2AX; H2A Histone Family; Member X
Gene ID 15270
UniProt ID P27661

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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