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Mouse Growth Regulated Oncogene Gamma (GROγ) ELISA Kit-Sandwich

Cat. No.EK5F66

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Growth Regulated Oncogene Gamma (GROγ) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GROγ in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Growth Regulated Oncogene Gamma (GROγ).
Target Species Mouse
Species Reactivity Mouse
Detection Range 78.25-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Growth Regulated Proteins (GRO) consist of three proteins: GRO-α, GRO-β, and GRO-γ. GRO-γ, also known as CXCL3, interacts with the chemokine receptor CXCR2 to facilitate monocyte migration and adhesion. The functions of GRO-β and GRO-γ are not limited by species, as they are effective on both rat and human neutrophils, and their activity can be inhibited by antibodies targeting CINC, the rat homolog of GRO. GROγ indirectly supports tumor growth and metastasis by promoting endothelial cell migration and angiogenesis. For example, studies have shown that GROγ can induce endothelial cell migration and angiogenesis, thereby providing nutrients and oxygen to tumors.

Target/Biomarker Mouse GROγ
Target Synonym CXCL3; SCYB3; GRO3; GRO-G; MIP2-B; MIP2b; CINC2b; CINC2b; Chemokine(C-X-C-Motif)ligand 3; Macrophage inflammatory protein 2-beta

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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