Mouse Growth Hormone (GH) ELISA Kit-Sandwich

Growth Hormone (GH) is crucial for growth regulation, primarily by stimulating the liver and other tissues to produce insulin-like growth factor-1 (IGF-1). This hormone promotes the differentiation and proliferation of myoblasts and enhances amino acid uptake and protein synthesis in muscle and other tissues. GH is vital for regulating growth and development, exerting its effects through the promotion of IGF-1 expression. GH deficiency can result in growth retardation and short stature, as evidenced by mice with a deletion of the growth hormone receptor gene (GHR-KO), which exhibit significant growth delays, with reduced weight and body length compared to normal mice. Additionally, GH influences body composition by promoting the breakdown of adipose tissue and the synthesis of muscle. Consequently, GH deficiency can lead to increased adipose tissue and reduced lean body mass.