Mouse Gonadotropin Inhibitory Hormone (GnIH) ELISA Kit-Competitive

Gonadotropin Inhibitory Hormone (GnIH) serves as a crucial neuromodulator in mammals. Its primary role is to regulate reproductive axis activity by inhibiting the secretion of gonadotropin-releasing hormone (GnRH). Produced in the hypothalamus, GnIH is a neuropeptide that can directly impact the anterior pituitary to suppress the release of gonadotropins, including luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In mice, GnIH reduces GnRH release through its receptor, GPR147, thereby lowering the secretion of LH and FSH from the pituitary. Moreover, GnIH indirectly influences the reproductive system by affecting gonad development and maintenance. In mice, GnIH not only suppresses pituitary gonadotropin secretion but also plays a role in the reproductive process by modulating gonadal development and function.