This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Glycine Dehydrogenase (GLDC) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Glycine Dehydrogenase (GLDC) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GLDC in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The glycine cleavage system facilitates the breakdown of glycine. The P protein (GLDC) attaches to the alpha-amino group of glycine using its pyridoxal phosphate cofactor, releasing CO2. The remaining methylamine group is transferred to the lipoamide cofactor of the H protein (GCSH). In mice, GLDC is involved not only in glycine metabolism but also in neural tube closure, folate metabolism, kidney development, and various physiological and pathological processes. Mouse models lacking GLDC, created through gene knockout techniques like GldcGT1/GT1, exhibit severe developmental issues, including craniofacial neural tube defects, hydrocephalus, growth retardation, and early death.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.