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Mouse Glutathione S Transferase Omega 1 (GSTo1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Glutathione S Transferase Omega 1 (GSTo1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GSTo1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Glutathione S-transferase omega-1 (GSTO1) exhibits several enzymatic activities, including glutathione-dependent thiol transferase, dehydroascorbate reductase, and S-(phenacyl)glutathione reductase activities. It also possesses glutathione S-transferase activity. GSTO1 participates in the biotransformation of inorganic arsenic, reducing monomethylarsonic acid (MMA) and dimethylarsonic acid. In mice, GSTO1 serves various biological functions, such as antioxidant defense, inflammation regulation, and cell survival pathway regulation, while also engaging in metabolic and biotransformation processes. As an omega-type glutathione transferase, GSTO1 catalyzes the reduction of monomethylarsenate, the rate-limiting step in arsenic biotransformation. Additionally, GSTO1 is involved in regulating the release of intracellular calcium ions, protecting cells from apoptosis due to calcium ion overload by influencing the activity of Ryanodine receptors (RyR1) in skeletal muscle.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.