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Mouse Glutamate Decarboxylase 2, Acid (GAD2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Glutamate Decarboxylase 2, Acid (GAD2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GAD2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The neurotransmitter GABA is essential for maintaining the balance between excitatory and inhibitory signaling in the brain. Disruptions in its synthesis or regulation are linked to various behavioral abnormalities, including those seen in autism spectrum disorder (ASD). Glutamate Decarboxylase 2, Acid serves to catalyze the production of GABA. In a mouse model, gestational diabetes mellitus can influence the expression of the GAD2 gene by altering the methylation status of its promoter region in the prefrontal cortex of male offspring, potentially leading to dysfunction in the GABAergic system in these males.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Liu, Xuan-Qi et al. "Gestational diabetes induces autistic-like behaviors in offspring by disrupting the GABAergic system." Frontiers in neuroscience vol. 19 1538115. 12 Feb. 2025.