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Mouse Glucokinase (GCK) ELISA Kit-Sandwich

Cat. No.EK5F530

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Glucokinase (GCK) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GCK in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Glucokinase (GCK).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Hexokinase-4 facilitates the phosphorylation of hexoses like D-glucose, D-fructose, and D-mannose, transforming them into hexose 6-phosphate. Unlike other hexokinases, hexokinase-4 exhibits a lower affinity for D-glucose and functions effectively only when glucose is plentiful. It is predominantly expressed in pancreatic beta cells and the liver, where it serves as a rate-limiting step in glucose metabolism. In mice, hexokinase-4 is primarily involved in glucose metabolism and immune regulation, with research supporting its role in glycogen synthesis, energy metabolism, and immune responses.

Target/Biomarker Mouse GCK
Target Synonym GK; GLK; HHF3; HK4; HKIV; HXKP; MODY2; Hexokinase-D; Hexokinase 4; Maturity Onset Diabetes Of The Young 2
Gene ID 103988
UniProt ID P52792

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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