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Mouse Glial Fibrillary Acidic Protein (GFAP) ELISA Kit-Sandwich

Cat. No.EK5F327

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Glial Fibrillary Acidic Protein (GFAP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GFAP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Glial Fibrillary Acidic Protein (GFAP).
Target Species Mouse
Species Reactivity Mouse
Detection Range 62.5-4000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Glial fibrillary acidic protein (GFAP), a class-III intermediate filament, serves as a cell-specific marker that distinguishes astrocytes from other glial cells during central nervous system development. As the primary intermediate filament protein in astrocytes, GFAP is not only expressed in these cells but also interacts with neurons. For instance, GFAP-deficient mice exhibit enhanced long-term potentiation (LTP), highlighting GFAP's significant role in regulating synaptic function and neuron-glial cell interactions. Additionally, GFAP-deficient mice show larger cerebral infarct volumes and more severe neurological dysfunction following brain injury.

Target/Biomarker Mouse GFAP
Target Synonym Intermediate Filament Protein
Gene ID 14580
UniProt ID P03995

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Järlestedt, Katarina et al. "Attenuation of reactive gliosis does not affect infarct volume in neonatal hypoxic-ischemic brain injury in mice." PloS one vol. 5,4 e10397. 28 Apr. 2010.
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