Mouse Gap Junction Beta-6 Protein (Gjb6) ELISA Kit-Sandwich

Gap junction beta-6 protein forms a part of gap junctions, which are clusters of tightly packed pairs of transmembrane channels, known as connexons. These channels facilitate the diffusion of low molecular weight materials between neighboring cells. In mice, GJB6 is primarily involved in intercellular communication, tissue homeostasis, pregnancy-related changes, and auditory function regulation. Notably, GJB6 is highly expressed in the corneal reticular layer, where aqueous humor flows, indicating its crucial role in ocular tissues, particularly in maintaining aqueous humor flow and ensuring intercellular communication. Additionally, the expression of GJB6 in mouse brain tissue correlates with the differentiation and functional status of glial cells. Research has shown high GJB6 expression in G2 phase glial cells, suggesting its involvement in cell cycle regulation.