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Mouse G Protein Beta 1 (GNb1) ELISA Kit-Sandwich

Cat. No.EK5F973

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse G Protein Beta 1 (GNb1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GNb1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse G Protein Beta 1 (GNb1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Guanine nucleotide-binding proteins (G proteins) function as modulators or transducers in various transmembrane signaling systems. The beta and gamma chains are essential for GTPase activity, the exchange of GDP for GTP, and G protein-effector interaction. In mice, GNB1 plays crucial roles in neurodevelopment, neurodegenerative diseases, the visual system, emotion regulation, and neurotransmitter signaling. Disruptions in these functions can lead to various diseases, such as neurodevelopmental disorders, epilepsy, and retinal degeneration. The GNB1 gene is vital for mouse embryonic development, with its deficiency potentially causing embryonic lethal defects like neural tube closure failure and microcephaly.

Target/Biomarker Mouse GNb1
Target Synonym GN-B1; Guanine Nucleotide Binding Protein Beta 1; Transducin beta chain 1
Gene ID 14688
UniProt ID P62874

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Malerba, Natascia et al. "The Emerging Role of Gβ Subunits in Human Genetic Diseases." Cells vol. 8,12 1567. 4 Dec. 2019.
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