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Mouse FK506 Binding Protein 1B (FKBP1B) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse FK506 Binding Protein 1B (FKBP1B) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FKBP1B in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Peptidyl-prolyl cis-trans isomerase FKBP1B may contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. These isomerases, known as PPIases, accelerate protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. In mice, FKBP1B functions primarily in neurons, where it regulates neuronal activity by modulating calcium ion release. The protein encoded by the FKBP1B gene releases calcium ions from the endoplasmic reticulum and lysosomes, a process influenced by short peptide treatment. Activation of FKBP1B gene transcription leads to increased synthesis of its protein product, which enhances calcium ion release and subsequently improves neuronal functional activity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.