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Mouse Filaggrin (FLG) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Filaggrin (FLG) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FLG in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Filaggrin is responsible for aggregating keratin intermediate filaments and promoting disulfide-bond formation among them during the terminal differentiation of mammalian epidermis. In mice, filaggrin primarily contributes to the formation and maintenance of the skin barrier and is also implicated in the development of related skin diseases. Besides its crucial role in the skin barrier, filaggrin influences the immune system. Research indicates that filaggrin-deficient mice show an increased accumulation of γδ T cells in the thymus, along with elevated levels of inflammatory factors like IL-17A.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Jee, Mia Hamilton et al. "Increased Production of IL-17A-Producing γδ T Cells in the Thymus of Filaggrin-Deficient Mice." Frontiers in immunology vol. 9 988. 8 May. 2018.