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Mouse Fibroblast Growth Factor Receptor 4 (FGFR4) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Fibroblast Growth Factor Receptor 4 (FGFR4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FGFR4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Fibroblast growth factor receptor 4 (FGFR4) is a tyrosine-protein kinase that functions as a cell-surface receptor for fibroblast growth factors. It is involved in regulating cell proliferation, differentiation, and migration, as well as lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism, and phosphate homeostasis. FGFR4-deficient mice (FGFR4−/−) display an enlarged bile acid pool, increased expression of cholesterol 7α-hydroxylase (CYP7A1), and elevated bile acid synthesis. These findings suggest that FGFR4 plays a crucial role in maintaining metabolic homeostasis by negatively regulating bile acid synthesis in the liver.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.