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Mouse Fibrinogen Like Protein 2 (FGL2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Fibrinogen Like Protein 2 (FGL2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FGL2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Fibroleukin (FGL2) can transform prothrombin into thrombin and serves multiple roles in mice, including immunoregulation, antiviral defense, inflammation control, and cardiovascular and metabolic functions. As an immunomodulatory molecule, FGL2 is secreted by regulatory T cells (Tregs) and has a notable immunosuppressive impact. It achieves its immunosuppressive effects by binding to Fcγ receptors, like FcγRIIB and FcγRIII, thereby inhibiting dendritic cell maturation and T cell proliferation. For instance, in a mouse liver transplantation model, overexpression of FGL2 enhances transplant tolerance, whereas mice lacking FGL2 exhibit poor transplant outcomes.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.