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Mouse Family With Sequence Similarity 3, Member B (FAM3B) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Family With Sequence Similarity 3, Member B (FAM3B) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FAM3B in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Protein FAM3B induces apoptosis in alpha and beta cells in a dose- and time-dependent manner. It is expressed in pancreatic β cells and co-secreted with insulin. Research indicates that FAM3B plays a significant role in the development of insulin resistance and type 2 diabetes by inducing apoptosis of pancreatic β cells and affecting insulin secretion. For instance, overexpression of FAM3B results in increased apoptosis of pancreatic β cells and reduced insulin secretion, whereas FAM3B knockout mice demonstrate improved insulin sensitivity and glucose tolerance.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Meng, Yuhuan et al. "Integrative Analysis of Genome and Expression Profile Data Reveals the Genetic Mechanism of the Diabetic Pathogenesis in Goto Kakizaki (GK) Rats." Frontiers in genetics vol. 9 724. 10 Jan. 2019.