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Mouse Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit-Sandwich

Cat. No.EK5F143

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Extracellular Signal Regulated Kinase 1 (ERK1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ERK1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Extracellular Signal Regulated Kinase 1 (ERK1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 6.86-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Extracellular Signal-Regulated Kinase 1, also known as Mitogen-Activated Protein Kinase 3, is a serine/threonine kinase that plays a critical role in the MAP kinase signal transduction pathway. The two mitogen-activated protein kinases (MAPKs) involved, MAPK1/ERK2 and MAPK3/ERK1, are key players in the MAPK/ERK cascade. The MEK1-ERK1 signaling pathway is significantly involved in cardiac hypertrophy. Research has demonstrated that MEK1 transgenic mice display focused hypertrophy of cardiomyocytes without the development of cardiomyopathy or heart failure, indicating that the ERK1/2 signaling pathway may serve a protective function in adaptive cardiac hypertrophy.

Target/Biomarker Mouse ERK1
Target Synonym HS44KDAP; HUMKER1A; P44ERK1; P44MAPK; PRKM3; MAPK3; ERT2; Mitogen-Activated Protein Kinase 3; Insulin-stimulated MAP2 kinase; Microtubule-associated protein 2 kinase
Gene ID 26417
UniProt ID Q63844

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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